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    Bio Sensor
    Bio Sensor Bio Sensor
    Bio Sensor Bio Sensor

    Bio Sensor

    ​A biosensor is an analytical device, used for the detection of an analyte , that combines a biological component with a physicochemical detector. The sensitive biological element is a biologically derived material or biomimetic component that interacts (binds or recognizes) with the analyte under study.

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    A biosensor is an analytical device, used for the detection of an analyte , that combines a biological component with a physicochemical detector. The sensitive biological element is a biologically derived material or biomimetic component that interacts (binds or recognizes) with the analyte under study. The biologically sensitive elements can also be created by biological engineering. The transducer or the detector element (works in a physicochemical way; optical, piezoelectric, electrochemical, etc.) transforms the signal resulting from the interaction of the analyte with the biological element into another signal (i.e., transduces) that can be more easily measured and quantified. The biosensor reader device with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way. We are usually custom-designed and manufactured to suit the different working principles of biosensors.


    Key Advantages of Quartz Crystal Microbalance Biosensor

    Quartz crystal microbalance biosensors provide several important benefits:

    Label-free detection
    No need for fluorescent or chemical labels

    Real-time monitoring
    Enables continuous observation of binding interactions

    Ultra-high sensitivity
    Detects minute mass variations with high precision

    Broad compatibility
    Suitable for biological, chemical, and environmental targets

    Reliable and repeatable performance
    High-quality quartz ensures consistent results


    Applications of Quartz Crystal Microbalance Biosensor

    Quartz crystal microbalance biosensors are widely used across multiple industries:

    Biomedical and Clinical Diagnostics

    Detection of proteins, biomarkers, and pathogens

    Immunoassays and disease diagnostics

    Drug interaction and binding studies

    Environmental Monitoring

    Detection of pollutants and toxic substances

    Water and air quality analysis

    Food Safety and Quality Control

    Identification of bacteria, allergens, and contaminants

    Monitoring of food processing conditions

    Surface Science and Material Research

    Thin film deposition analysis

    Adsorption and desorption studies

    Coating performance evaluation 


    Bio Sensor

    Conclusion

    Quartz crystal microbalance biosensors combine the precision of quartz crystal technology with the specificity of biological recognition, enabling highly sensitive and real-time detection of mass changes. Their reliability, versatility, and accuracy make them a key technology in modern analytical applications.

    As demand continues to grow for fast and precise detection methods, quartz crystal microbalance biosensors will remain an important solution in scientific research, healthcare, and industrial monitoring.


    our running series typical chips

    Bio-Sensors Chips


    The following spec sheet is a typical one, you may freely tell us and we’ll pleased to customize them for you.

    Bio-Sensors Chips

    Quantity More than 1.5 million monthly
    Cut Type Thickness Shear Mode (TSM)
    Nominal Frequency 16.5 MHz +/- 165KHz
    Crystal Cutting 35 degrees 15' +/- 3' (AT cut)
    Operating Temperature 37º C +/- 2º C
    Footprint Size 8.6 +/- 0.05 mm x 5.4 +/- 0.05 mm, see drawing1
    Bottom Side 3 1.7 mm diameter
    Number of Electrodes
    Electrode Size
    Top Side 18.6 mm x 5.4 mm
    Number of Electrodes
    Electrode Size
    Electrode Plating 10nm Chromium Layer90nm Gold Layer
    Shear force≥7g
    Deposition Rate

    0.8 nms-1 at nominal room temperature

    Aging frequency drift at 25 degrees: ≤2%

    Temperature frequency shift (how much can the frequency change 

    over the operating temperature range of 35 to 39 degrees)

    as low as possible (e.g. << 1 ppm)
    Storage temperature rangeassume similar range for IVD device (e.g. 2 °C to 30 °C)
    Shunt capacitance and load capacitance spec no preference
    Voltage which it will be drivenin the 100s mV range
    Drive level amount of power that will be dissipatedno preference
    Insulation resistance expect less than 200 ohms, see drawing 2
    ESR (equivalent series resistance)low ESR and high quality factor
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